Anderlechts Europa League campaign came to an end after a 2-0 defeat at Fenerbahce on Thursday.
With two games to go, the Belgian side has no chance of reaching the knockout stage on one point.
Anderlecht is playing in the group stage of Europes second tier competition for the sixth time, and previously advanced to the knockout round each time. It reached the quarterfinals in 2017.
Mathieu Valbuena and Michael Frey scored in the second half for Fenerbahce.